ANTIBIOTIC RESISTANCE OF MICROBIAL COMMUNITIES IN CATTLE WITH MORTELLARO DISEASE AND RUSTERGOLTS ULCERстатья из журнала
Аннотация: The widespread and frequent recurrence of limb diseases in cattle results from the irrational use of antibiotics and lack of knowledge about the qualitative composition of microorganisms living in wound surfaces. The issue of increasing the effectiveness of therapeutic and preventive measures against the cattle limb diseases must be addressed using an approach that takes into account the characteristics of the qualitative composition of microbiocenoses and their resistance to antibiotic and antimicrobial substances. The studies were conducted in 2018–2022. They focused on the microbial composition and sensitivity to antibiotic and antimicrobial substances in Holstein cattle with an average milk production of 10,500 kg. The disk diffusion method was used to test sensitivity of bacteria to an extended spectrum of antibiotics (amoxiclav, ampicillin + sulbactam, gentamicin, levofloxacin, oxacillin, ofloxacin, tetracycline, chloramphenicol, fosfomycin, cefazolin, cefotaxime, ceftriaxone, ciprofloxacin, erythromycin) in accordance with methodological guidelines MUK 4.2.1890-04. The sensitivity of fungi to antimycotics (amphocetrin, itraconazole, caspofungin, ketoconazole, clotrimazole, miconazole, nystatin, flucytosine, fluconazole, econazole) was studied using the disk diffusion method. The study aimed to test the antibiotic resistance of microbial communities in cattle with Mortellaro disease and Rustergolts ulcer. The study has found that the microbial communities of wound surfaces formed in Mortellaro disease and Rusterholtz ulcer are inoculated with 13 types of microorganisms that are sensitive to antibiotic and antimicrobial drugs. Most of the identified bacteria (except for Klebsiella pneumonia, Streptococcus spp. and Enterococcus spp.) proved insensitive to tetracycline antibiotics. The greatest spectrum of antibiotic resistance was found in Enterobacter cloacea and Enterobacter sakosaki: most strains proved insensitive to amoxiclav, gentamicin, levofloxacin, ofloxacin, tetracycline, cefazolin, cefotaxime, ceftriaxone and ciprofloxacin. Yeast-like fungi Candida albicans were insensitive to amphocetrin, nystatin, flucytosine, caspofungin, and Candida krusei to caspofungin and miconazole.
Год издания: 2023
Источник: VESTNIK OF THE BASHKIR STATE AGRARIAN UNIVERSITY
Ключевые слова: Agriculture and Biological Studies
Открытый доступ: gold
Том: 68
Выпуск: 4
Страницы: 76–81