Аннотация:Introduction: Mandibular fractures are considered the most common facial bonesfractures. Treating mandibular fractures is difficult due to probability of complications,and there is presently no consensus on the best therapy. Aim: This study aimed toevaluate the role of xeno-hydroxyapetite bone graft in the healing of unfavorableoblique mandibular fractures under rigid fixation. Material and methods: Thisexperimental study included 18 healthy male dogs. Unilateral mandibular fractureswere induced for all animals. Animals were divided equally into: Control group (I)where the fracture was fixed with reconstruction bone plate only. Study group (II) wherethe fracture was fixed with reconstruction bone plate and bone defect was filled with thexeno-hydroxyapetite bone graft. The bone defect site was examined radiographically,Histopathologically and histomorphometrically at 2, 4 and 8 weeks. Results: There wassignificant increase in bone density with increasing time in both groups. The analysis ofhistological sections revealed that the newly formed bony spicules in both groups werelocalized randomly and in discrete puncta within the graft material. Histomorphometryanalysis suggests that the bovine bone graft showed well-organized and reconstructedbone similar to native bone tissues. Conclusion: Xeno-hydroxyapetite bone graft is agood choice for the jaw bone reconstruction and can reduce the healing time in the areaof the fracture line. Xeno-hydroxyapetite bone graft can be satisfactorily used as graftsin the treatment of unfavorable mandibular fractures.
