Editorialредакционная статья
Аннотация: Non-communicable diseases (NCD) have been on the rise, representing 60% of all deaths in the world.Cardiovascular diseases (CVD), one of the NCD, are the leading cause of death globally, taking an estimated 17.9 million lives each year.Due to cholesterol lowering effect, sterols are considered to be effective in the prevention of CVD.Tea is one of the most popular beverages consumed worldwide and is ranked at a level of being the second non-alcoholic drink after water.It is, therefore, of great importance to develop sterol-enriched functional beverage that helps prevention of CVD.We developed a sterol-enriched functional black tea (functional ice tea).A randomized, double-blind, placebocontrolled human clinical trial was conducted on volunteer subjects (n = 90) aged 25-60 year with mild hypercholesterolemia. Subjects were randomly divided into placebo (n = 33; M/F ratio 23/10), instant black tea (n = 34; M/F ratio 25/9), and functional black tea (2 g sterols/day) (n = 32; M/F ratio 24/8) groups and intervention period was conducted for 4 weeks.Compared with baseline, consumption of functional black tea significantly decreased the concentrations of total cholesterol by 5.6% (P < 0.001), low-density lipoprotein cholesterol by 8.7% (P < 0.001), apolipoprotein B (P < 0.05), and oxidative stress index (P < 0.05), while increasing the concentrations of adiponectin, total antioxidant status, and tissue-plasminogen activator (P < 0.05).Functional black tea was superior to instant black tea in terms of cardiovascular risk biomarkers.The data indicate that consumption of newly developed product is an excellent beverage for delivering sterols and has several beneficial cardio-protective effects in subjects with mild hypercholesterolemia. Health claims on sterols and sterol enriched beverages in the market will also be presented.
Год издания: 2023
Авторы: Vladimir Morocho, Ahmet C. Gören, Mehmet Öztürk
Издательство: ACG Publications
Источник: Records of Agricultural and Food Chemistry
Открытый доступ: bronze
Выпуск: S
Страницы: 1–63