Аннотация:decrease in the glomerular filtration rate would constitute clinical tumor lysis syndrome (see Table 1 of our article).Removal of a 25% change from the definition by Cairo and Bishop applies only to uric acid, phosphorus, potassium, and calcium.The lack of randomized studies precludes definitive recommendation of a specific diuretic.For now, the rat model provides the only available data, and furosemide has proved effective in our practice.