Аннотация:Immunodeficiency sets the stage for human herpesvirus 8 (HHV-8) infection, which can lead to Kaposi sarcoma.Compared with the general population, HHV-8 infection is common in HIV-positive individuals and in men who have sex with men (MSM).Those associations are corroborated by the present meta-analysis, which also shows that HHV-8 seroprevalence is highest in MSM and in children.Sexual transmission of HIV and HHV-8 is likely in MSM.In children, who typically acquire HHV-8 via nonsexual transmission, infection may occur as a result of HHV-8 shedding from HIV-positive family members.Further studies are needed to clarify HHV-8 transmission routes.
