Substitution of Expensive Protein Sources by Soybean Meal Supplemented with a β-Mannanase Enzyme Results in Improved General Clinical Health Score during the Post-Weaning Period
Аннотация:oxygen and nitrogen species, bacteriolytic enzymes, antimicrobial peptides and complement proteins [5].These PAMP include complex polysaccharides such as β-mannan [4].Therefore, β-mannans from feed can create a false signal about the presence of pathogens in the gut, that elicits an unwarranted immune activation [6,7], which is also known as a feed induced immune response (FIIR).The recognition of β-mannans elicits a futile immune response that causes energy and nutrients to be wasted [3].Hydrolysis of these β-mannans by dietary inclusion of an exogenous β-mannanase enzyme can reduce and potentially eliminate their ability to induce FIIR.Supplementation of β-mannanase to low-and high-mannan diets has the potential to improve the performance of growing pigs [8].Moreover, ingredients with high β-mannan content like palm kernel meal (PKM) or copra meal may partially replace SBM without reducing pig performance if β-mannanase is supplemented to the diet [8,9].Some researchers have suggested that the improved pig performance following β-mannanase supplementation to corn-SBM-PKM diets might be due to increased ileal digestibility of different amino acids [10][11][12].Others concluded that β-mannanase improved growth performance in both weanling and growing-finishing pigs on corn-SBM diets [13][14][15] with minimal effects on nutrient digestibility
