Аннотация:To the Editor:Coronavirus disease (COVID-19) is a novel illness and is a rapidly evolving pandemic with unprecedented impact on global health in the last 100 years (1).At the time of submission of this work, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused 130 million diagnosed infections and 2.8 million known deaths.Although vaccines are currently developed and are now broadly used in public health prevention measures, the treatment options for patients with COVID-19 are sparse and do not show sufficient efficacy (2).SARS-CoV-2 uses several host factors to infect target cells, including TMPRSS2 (transmembrane protease serine 2), for activation of the viral