Sleep and vital exhaustion : their relationship with cardiovascular diseasedissertation
Аннотация: This thesis explores two potential risk indicators for myocardial infarction (MI): disturbed sleep and a state of vital exhaustion (VE).In chapter 1, a general background is given for the studies to be presented in this thesis-In chapter 2, the development and validation is described of the Sleep-Wake Experience List (SWEL), a questionnaire for the detection of six distinct types of sleep complaints.The results showed that the quality of the SWEL as a screening instrument ranges from 52.3-90.3%.The quality of this questionnaire as a diagnostic and prognostic instrument ranges from 51.1-78.0%.In chapter 3, the question is raised whether an association of VE with these sleep complaints, habitual sleep durations, napping, and snoring is confounded by the Type A coronary prone behaviour pattern (TABP) and vice-versa.It appeared that exhausted subjects report sleep problems, a short habitual sleep, and frequent napping significantly more often than nonexhausted subjects.TABP did not confound these associations.This suggests that these various subjective sleep characteristics can be understood as risk indicators for MI by their association with VE.Some caution for this conclusion is required, however, because VE shares a number of symptoms with depression, a condition that is closely tied to a disturbed sleep.In chapter 4, therefore, a study is presented that explored whether VE is characterized by a depressed mood or by a loss of vigour and excess fatigue.The results indicated that depression is not a likely reason for exhausted subjects to complain about their sleep because the key symptom for depressive disorders, a depressed mood, is not among the major characteristics of VE.Chapter 5 focusses on a possible discrepancy in the perception of the habitual quality and current night quality of sleep.It appeared that exhausted subjects perceive both their habitual and their current sleep as more disturbed than non-exhausted subjects.The results further suggested that exhausted subjects do not base their sleep quality entirely upon time spent asleep or upon the length of nocturnal wake times.In chapter 6, we hypothesized that the sleep of exhausted subjects is characterized by a relative absence of slow wave sleep (SWS).To test this hypothesis, all-night sleep recordings of exhausted and nonexhausted subjects were analyzed visually, by an automatic system, and by spectral analysis.It appeared that EEG-derived awake times of exhausted subjects were not significantly different from those of non-exhausted subjects.However, both visual and spectral analysis of sleep converged to the conclusion that the sleep of exhausted subjects is characterized by a reduced SWS.Chapter 7 concludes the thesis by presenting a review of the findings and a discussion of their implications for the study of sleep, vital exhaustion and future MI.-7-l>'isö,a|.s .f jIVï-Hóifeögff^a StJr/ ' M-sJbL-<; bag qa-ü
Год издания: 1993
Авторы: Rob van Diest
Ключевые слова: Sleep and related disorders, Sleep and Work-Related Fatigue, Heart Rate Variability and Autonomic Control
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