Аннотация:The article presents data on the prevalence of viral hepatitis B and C in 6 St. Petersburg multidisciplinary hospitals in 2005 -2010 on the results of laboratory tests for the same period, taking into account an annual sample of 185,211 people. The most intense epidemic process of hepatitis И was found in staff and inpatients of hemodialysis units. Among the staff and the surgical inpatients the incidence of viral hepatitis B and C was 7 times smaller than that in inpatients and staff of hemodialysis units. In therapeutic departments the rate of viral hepatitis was 2-4 times lower. The high level of HBsAg and other markers of hepatitis B and anti-HCV has been detected in inpatients in gastroenterological departments, extremely rare - in the staff.