1. Главная
  2. Ресурсы
  3. Библиотечный поиск
Transcatheter AorticValve Replacement inBicuspid Aortic ValveStenosis Flavien VincentJulien TernacleTom Denimal2021 год

Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Stenosis
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: After 15 years of successive randomized, controlled trials, indications for transcatheter aortic valve replacement (TAVR) are rapidly expanding. In the coming years, this procedure could become the first line treatment for patients with a symptomatic severe aortic stenosis and a tricuspid aortic valve anatomy. However, randomized, controlled trials have excluded bicuspid aortic valve (BAV), which is the most frequent congenital heart disease occurring in 1% to 2% of the total population and representing at least 25% of patients 80 years of age or older referred for aortic valve replacement. The use of a less invasive transcatheter therapy in this elderly population became rapidly attractive, and approximately 10% of patients currently undergoing TAVR have a BAV. The U.S. Food and Drug Administration and the "European Conformity" have approved TAVR for low-risk patients regardless of the aortic valve anatomy whereas international guidelines recommend surgical replacement in BAV populations. Given this progressive expansion of TAVR toward younger and lower-risk patients, heart teams are encountering BAV patients more frequently, while the ability of this therapy to treat such a challenging anatomy remains uncertain. This review will address the singularity of BAV anatomy and associated technical challenges for the TAVR procedure. We will examine and summarize available clinical evidence and highlight critical knowledge gaps regarding TAVR utilization in BAV patients. We will provide a comprehensive overview of the role of computed tomography scans in the diagnosis, and classification of BAV and TAVR procedure planning. Overall, we will offer an integrated framework for understanding the current role of TAVR in the treatment of bicuspid aortic stenosis and for guiding physicians in clinical decision-making.
Год издания: 2021
Авторы: Flavien Vincent, Julien Ternacle, Tom Denimal, Mylène Shen, Björn Redfors, Cédric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, François Pontana, Vinod H. Thourani, Philippe Pîbarot, Éric Van Belle
Издательство: Lippincott Williams & Wilkins
Источник: Circulation
Ключевые слова: Cardiac Valve Diseases and Treatments, Aortic Disease and Treatment Approaches, Infective Endocarditis Diagnosis and Management
Другие ссылки: Circulation (PDF)
Circulation (HTML)
hal.science (PDF)
hal.science (HTML)
PubMed (HTML)