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Nanoformulations ofHerbal Extracts inTreatment ofNeurodegenerativeDisorders Seyed Zachariah MoradiSaeideh MomtazZahra Bayrami2020 год

Nanoformulations of Herbal Extracts in Treatment of Neurodegenerative Disorders
review

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Аннотация: Nanotechnology is one of the methods that have been able to influence human life in different ways and is a substantial tool that assists to overcome the multiple limitations in the treatment of various diseases, especially neurodegenerative disorders (NDs). Various nanostructures such as polymer nanoparticles, lipid nanoparticles, nanoliposomes, nano-micelle, carbon nanotubes (CNTs), besides different vehicle systems including poly lactic-co-glycolic acid, lactoferrin, polybutylcyanoacrylate and some others significantly increased the effectiveness, reduced the side effects, enhanced the stability, and improved the pharmacokinetics of several drugs. NDs belong to a group of annoying and debilitating disorders involving millions of people worldwide. Privious studies revealed that several nano formulations from a number of natural products such as curcumin (Cur), quercetin (QC), resveratrol (RSV), piperine (PIP), Ginkgo biloba, and Nigella sativa showed significant effectiveness in improving the condition of patients with NDs. The blood-brain barrier (BBB) is the main limitation of NDs management. In this review, we have attempted to discuss the effects of herbal-based nano formulation that used to treat such diseases. In summary, herbal-based nanoformulations seem to be significant in the treatment of NDs, alone or in combination with other drugs.
Год издания: 2020
Авторы: Seyed Zachariah Moradi, Saeideh Momtaz, Zahra Bayrami, Mohammad Hosein Farzaei, Mohammad Abdollahi
Издательство: Frontiers Media
Источник: Frontiers in Bioengineering and Biotechnology
Ключевые слова: Medicinal Plants and Neuroprotection, Alzheimer's disease research and treatments, Ginkgo biloba and Cashew Applications
Другие ссылки: Frontiers in Bioengineering and Biotechnology (PDF)
Frontiers in Bioengineering and Biotechnology (HTML)
DOAJ (DOAJ: Directory of Open Access Journals) (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
PubMed (HTML)