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Biological VersusChronological Aging Magda R. HamczykRosa M. NevadoAna Barettino2020 год

Biological Versus Chronological Aging
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Aging is the main risk factor for vascular disease and ensuing cardiovascular and cerebrovascular events, the leading causes of death worldwide. In a progressively aging population, it is essential to develop early-life biomarkers that efficiently identify individuals who are at high risk of developing accelerated vascular damage, with the ultimate goal of improving primary prevention and reducing the health care and socioeconomic impact of age-related cardiovascular disease. Studies in experimental models and humans have identified 9 highly interconnected hallmark processes driving mammalian aging. However, strategies to extend health span and life span require understanding of interindividual differences in age-dependent functional decline, known as biological aging. This review summarizes the current knowledge on biological age biomarkers, factors influencing biological aging, and antiaging interventions, with a focus on vascular aspects of the aging process and its cardiovascular disease related manifestations.
Год издания: 2020
Авторы: Magda R. Hamczyk, Rosa M. Nevado, Ana Barettino, Valentı́n Fuster, Vicente Andrés
Издательство: Elsevier BV
Источник: Journal of the American College of Cardiology
Ключевые слова: Genetics, Aging, and Longevity in Model Organisms, Birth, Development, and Health, Diet and metabolism studies
Другие ссылки: Journal of the American College of Cardiology (HTML)
Biblos-e Archivo (Universidad Autónoma de Madrid) (PDF)
Biblos-e Archivo (Universidad Autónoma de Madrid) (HTML)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (PDF)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (HTML)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (PDF)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (HTML)
PubMed (HTML)