Аннотация:A woman in her 50s was admitted to our hospital with a history of melena and abdominal pain. Physical examination revealed no rebound tenderness in the abdomen, but abdominal computed tomography revealed a target-like appearance including the presence of a fat-density lesion in the descending colon. Colonoscopy revealed invagination of the descending colon by a lipoma. Based on these findings, the patient was diagnosed as having an intussusception. A standby emergency operation was performed. At laparoscopy, an intussusception was found on the descending colon. Partial resection of the left side of the colon was performed. The histological diagnosis confirmed a benign lipoma. After operation the patient remains well. An intussusception caused by a lipoma might be treated with laparoscopic surgery in the case of stable patients requiring surgical intervention.