Burden of influenza-associated respiratory hospitalizations in the Americas, 2010–2015статья из журнала
Аннотация: Despite having influenza vaccination policies and programs, countries in the Americas underutilize seasonal influenza vaccine, in part because of insufficient evidence about severe influenza burden. We aimed to estimate the annual burden of influenza-associated respiratory hospitalizations in the Americas.Thirty-five countries in the Americas with national influenza surveillance were invited to provide monthly laboratory data and hospital discharges for respiratory illness (International Classification of Diseases 10th edition J codes 0-99) during 2010-2015. In three age-strata (<5, 5-64, and ≥65 years), we estimated the influenza-associated hospitalizations rate by multiplying the monthly number of respiratory hospitalizations by the monthly proportion of influenza-positive samples and dividing by the census population. We used random effects meta-analyses to pool age-group specific rates and extrapolated to countries that did not contribute data, using pooled rates stratified by age group and country characteristics found to be associated with rates.Sixteen of 35 countries (46%) contributed primary data to the analyses, representing 79% of the America's population. The average pooled rate of influenza-associated respiratory hospitalization was 90/100,000 population (95% confidence interval 61-132) among children aged <5 years, 21/100,000 population (13-32) among persons aged 5-64 years, and 141/100,000 population (95-211) among persons aged ≥65 years. We estimated the average annual number of influenza-associated respiratory hospitalizations in the Americas to be 772,000 (95% credible interval 716,000-829,000).Influenza-associated respiratory hospitalizations impose a heavy burden on health systems in the Americas. Countries in the Americas should use this information to justify investments in seasonal influenza vaccination-especially among young children and the elderly.
Год издания: 2019
Авторы: Rakhee Palekar, Melissa A. Rolfes, Carmen Sofia Arriola, Belsy Acosta, Patricia Alberto Guidos, Xiomara Badilla Vargas, Christina Bancej, Juliana Barbosa Ramírez, Elsa Baumeister, Alfredo Bruno, María Águeda Cabello, Jufu Chen, Paula Couto, Francisco José de Paula Júnior, Rodrigo Fasce, Walquiria Ferreira de Almeida, Victor E. Fiesta Solorzano, Carlos Flores Ramírez, Natalia Goñi, Yadira Isaza de Moltó, Jenny Lara, Diana Malo, José Medina, Homer Mejía, Lourdes Moreno Castillo, Desiree Mustaquim, Andrea Nwosu, Jenny Ojeda, Antonio Paredes Samoya, Paola Pulido, Hector M. Ramos Hernandez, Rudvelinda Rivera Lopez, Angel Rodríguez, Myriam Saboui, Hilda Bolaños, Adrián Santoro, Jose Eduardo Silvera, Paulina Sosa, Viviana Sotomayor, Lourdes Suárez, Marta Von Horoch, Eduardo Azziz‐Baumgartner
Издательство: Public Library of Science
Источник: PLoS ONE
Ключевые слова: Influenza Virus Research Studies, Respiratory viral infections research, Smoking Behavior and Cessation
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PLoS ONE (HTML)
DOAJ (DOAJ: Directory of Open Access Journals) (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
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Том: 14
Выпуск: 9
Страницы: e0221479–e0221479