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The Genetic Links toAnxiety andDepression (GLAD)Study: Onlinerecruitment into thelargest recontactablestudy of depressionand anxiety Molly R. DaviesGursharan KalsiChérie Armour2019 год

The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety
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Аннотация: Anxiety and depression are common, debilitating and costly. These disorders are influenced by multiple risk factors, from genes to psychological vulnerabilities and environmental stressors, but research is hampered by a lack of sufficiently large comprehensive studies. We are recruiting 40,000 individuals with lifetime depression or anxiety and broad assessment of risks to facilitate future research. The Genetic Links to Anxiety and Depression (GLAD) Study (www.gladstudy.org.uk) recruits individuals with depression or anxiety into the NIHR Mental Health BioResource. Participants invited to join the study (via media campaigns) provide demographic, environmental and genetic data, and consent for medical record linkage and recontact. Online recruitment was effective; 42,531 participants consented and 27,776 completed the questionnaire by end of July 2019. Participants' questionnaire data identified very high rates of recurrent depression, severe anxiety, and comorbidity. Participants reported high rates of treatment receipt. The age profile of the sample is biased toward young adults, with higher recruitment of females and the more educated, especially at younger ages. This paper describes the study methodology and descriptive data for GLAD, which represents a large, recontactable resource that will enable future research into risks, outcomes, and treatment for anxiety and depression.
Год издания: 2019
Авторы: Molly R. Davies, Gursharan Kalsi, Chérie Armour, Ian Jones, Andrew M. McIntosh, Daniel J. Smıth, James Walters, John R. Bradley, Nathalie Kingston, Sofie Ashford, Ioana Beange, Anamaria Brăilean, Anthony J. Cleare, Jonathan R. I. Coleman, Charles Curtis, Susannah C.B. Curzons, Katrina A. S. Davis, Le Roy C. Dowey, Victor A. Gault, Kimberley Goldsmith, Megan Hammond Bennett, Yoriko Hirose, Matthew Hotopf, Christopher Hübel, Carola Kanz, Jennifer Leng, Donald M. Lyall, Bethany D. Mason, Monika McAtarsney‐Kovacs, Dina Monssen, Alexei Moulton, Nigel Ovington, Elisavet Palaiologou, Carmine M. Pariante, Shivani Parikh, Alicia J. Peel, Ruth Price, Katharine A. Rimes, Henry C. Rogers, Jennifer Sambrook, Megan Skelton, Anna Spaul, Eddy L.A. Suarez, Bronte L. Sykes, Keith Thomas, Allan H. Young, Evangelos Vassos, David Veale, Katie M White, Janet Wingrove, Thalia C. Eley, Gerome Breen
Издательство: Elsevier BV
Источник: Behaviour Research and Therapy
Ключевые слова: Mental Health Research Topics, Child and Adolescent Psychosocial and Emotional Development, Mental Health Treatment and Access
Другие ссылки: Behaviour Research and Therapy (HTML)
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