The burden of chronic urticaria: French baseline data from the international real-life AWARE studyстатья из журнала
Аннотация: The AWARE study is an ongoing international study of patients with chronic urticaria refractory to H1-antihistamines. The aim of this study is to evaluate the burden of disease and the use of healthcare resources in real-life conditions. To analyse the baseline data of French patients included in the AWARE study. AWARE is a prospective, non-interventional, international study that includes adult patients who have had chronic urticaria, refractory to at least one H1-antihistamine, for at least two months. Ninety-four patients (mean age: 47.9 years; 71.3% women) with chronic urticaria (50.0% spontaneous only, 9.6% inducible only, and 40.4% both) were included in French centres. The median duration from diagnosis was three years and angioedema was present in 31.5% of patients for the past six months. In 63.8% of cases, the patients received at least one treatment for urticaria (H1-antihistamine for 66.0%). Chronic urticaria was poorly controlled (UCT score <12) in 88.9% of patients and quality of life was severely impaired (mean DLQI score: 8.6). The use of healthcare resources was significant with frequent visits to general practitioners (80.8% of patients; mean: 8.1 visits). However, more than half of patients had not previously consulted a dermatologist. These baseline data of French patients in the AWARE study show that patients suffering from chronic urticaria, refractory to H1-antihistamines for a median of three years, are insufficiently treated and that their quality of life is impaired. Despite the significant use of healthcare resources, access to specialised consultations remains insufficient.
Год издания: 2019
Авторы: G. Guillet, Pierre‐André Bécherel, P. Pralong, Marielle Delbarre, Omar Outtas, Laurent Martin, B. Pelvet, Hakam Gharbi, F. Giordano‐Labadie
Издательство: John Libbey Eurotext
Источник: European Journal of Dermatology
Ключевые слова: Urticaria and Related Conditions, Autoimmune Bullous Skin Diseases, Coagulation, Bradykinin, Polyphosphates, and Angioedema
Другие ссылки: European Journal of Dermatology (PDF)
European Journal of Dermatology (HTML)
PubMed (HTML)
European Journal of Dermatology (HTML)
PubMed (HTML)
Открытый доступ: bronze
Том: 29
Выпуск: 1
Страницы: 49–54