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DIAGNOSIS OFENDOCRINE DISEASE:Evaluation of bonefragility inendocrine disorders Cristina Eller-VainicherAlberto FalchettiLuigi Gennari2019 год

DIAGNOSIS OF ENDOCRINE DISEASE: Evaluation of bone fragility in endocrine disorders
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: An underlying disease affecting bone health is present in up to 40% and 60% of osteoporotic post-menopausal women and men respectively. Among the disorders leading to a secondary form of osteoporosis, the endocrine diseases are highly represented. A frequent finding in patients affected with an endocrine-related forms of bone disease is that the skeletal fragility is partially independent of the bone density, since the fracture risk in these patients is related more to a reduction of bone quality than to a decrease of bone mass. As a consequence, bone mineral density evaluation by dual-X-ray Absorptiometry may be inadequate for establishing the risk of fracture in the setting of the endocrine-related forms of osteoporosis. In the recent years several attempts to non-invasively estimating bone quality have been done. Nowadys, some new tools are available in the clinical practice for optimizing the fracture risk estimation in patients with endocrine disorders. The aim of this review is to summarise the evidences regarding the role of the different imaging tools for evaluating bone density and bone quality in the most frequent forms of endocrine-related osteoporosis, such as obesity, diabetes, acromegaly, thyrotoxicosis, primary hyperparathyroidism, hypercortisolism and hypogonadism. For each of these disorders, data regarding both the current available tools and the future possible new techniques for assessing bone fragility in patients with endocrine diseases are reported.
Год издания: 2019
Авторы: Cristina Eller-Vainicher, Alberto Falchetti, Luigi Gennari, Elisa Cairoli, Francesco Bertoldo, Fabio Vescini, Alfredo Scillitani, Iacopo Chiodini
Издательство: Oxford University Press
Источник: European Journal of Endocrinology
Ключевые слова: Bone health and osteoporosis research, Vitamin D Research Studies, Bone health and treatments
Другие ссылки: European Journal of Endocrinology (PDF)
European Journal of Endocrinology (HTML)
Use Siena air (University of Siena) (PDF)
Use Siena air (University of Siena) (HTML)
Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (PDF)
Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (HTML)
PubMed (HTML)