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Antimicrobial Effectsof BiogenicNanoparticles Priyanka SinghAbhroop GargSantosh Pandit2018 год

Antimicrobial Effects of Biogenic Nanoparticles
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Infectious diseases pose one of the greatest health challenges in the medical world. Though numerous antimicrobial drugs are commercially available, they often lack effectiveness against recently developed multidrug resistant (MDR) microorganisms. This results in high antibiotic dose administration and a need to develop new antibiotics, which in turn requires time, money, and labor investments. Recently, biogenic metallic nanoparticles have proven their effectiveness against MDR microorganisms, individually and in synergy with the current/conventional antibiotics. Importantly, biogenic nanoparticles are easy to produce, facile, biocompatible, and environmentally friendly in nature. In addition, biogenic nanoparticles are surrounded by capping layers, which provide them with biocompatibility and long-term stability. Moreover, these capping layers provide an active surface for interaction with biological components, facilitated by free active surface functional groups. These groups are available for modification, such as conjugation with antimicrobial drugs, genes, and peptides, in order to enhance their efficacy and delivery. This review summarizes the conventional antibiotic treatments and highlights the benefits of using nanoparticles in combating infectious diseases.
Год издания: 2018
Авторы: Priyanka Singh, Abhroop Garg, Santosh Pandit, V. R. S. S. Mokkapati, Ivan Mijakovic̀
Издательство: Multidisciplinary Digital Publishing Institute
Источник: Nanomaterials
Ключевые слова: Antimicrobial Peptides and Activities, Antimicrobial agents and applications, Bacterial biofilms and quorum sensing
Другие ссылки: Nanomaterials (PDF)
Nanomaterials (HTML)
DOAJ (DOAJ: Directory of Open Access Journals) (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (PDF)
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (HTML)
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (HTML)
Chalmers Research (Chalmers University of Technology) (PDF)
Chalmers Research (Chalmers University of Technology) (HTML)
PubMed Central (HTML)
PubMed (HTML)