Change in subfoveal choroidal thickness secondary to orthokeratology and its cessation: a predictor for the change in axial lengthстатья из журнала
Аннотация: Abstract Purpose To investigate changes in subfoveal choroidal thickness ( SFC hT) during orthokeratology (Ortho‐K) lens wear and after its cessation and the association of short‐term change in SFC hT with the long‐term eye elongation in Ortho‐K subjects. Design A prospective clinical trial. Methods Fifty myopic children aged between 9 and 14 years were enrolled. Twenty‐nine subjects continuously wore Ortho‐K lens for 12 months and discontinued for 1 month. Twenty‐one subjects wearing single vision distance spectacles for 12 months were included as the control group. SFC hT was assessed using optical coherence tomography. Ocular parameters, including axial length ( AL ), central corneal thickness ( CCT ), anterior chamber depth ( ACD ), lens thickness ( LT ) and apical corneal power ( ACP ), were also measured. Results After 12 months of follow‐up, AL elongation was larger and SFC hT change was smaller in the control group compared to the Ortho‐K group (both p < 0.001). In the Ortho‐K group, SFC hT increased by 16 μ m from baseline at the 1‐month visit (p < 0.001), and the magnitude of choroidal thickening remained unchanged at the 6‐ and 12‐month visit (p = 0.289). One month after discontinuation of Ortho‐K lens, SFC hT and ocular parameters of the anterior segment, including ACP , CCT and ACD recovered to baseline level (All p > 0.05), and AL increased by 0.23 ± 0.18 mm compared to baseline (p = 0.018). SFC hT change at 1‐month was negatively associated with AL change at 13‐month (standard β , −0.581, p = 0.001) after adjusting for other influencing factors, including baseline age and the ocular parameters. Conclusion Subfoveal ChT (SFChT) significantly increased after short‐term Ortho‐K lens treatment and the increase maintained throughout the period of treatment. One month after Ortho‐K lens cessation, SFC hT, ACP , CCT and ACD returned to baseline. Short‐term response in SFC hT is associated with long‐term change in AL in children undergoing Ortho‐K lens and may be a predictor for the effectiveness of the treatment.
Год издания: 2018
Авторы: Zhouyue Li, Yin Hu, Dongmei Cui, Long Wen, Mingguang He, Xiao Yang
Издательство: Wiley
Источник: Acta Ophthalmologica
Ключевые слова: Corneal surgery and disorders, Ophthalmology and Visual Impairment Studies, Retinal Diseases and Treatments
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Minerva Access (University of Melbourne) (PDF)
Minerva Access (University of Melbourne) (HTML)
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Том: 97
Выпуск: 3