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Detection of atrialfibrillation with asmartphone camera:first prospective,international,two-centre, clinicalvalidation study(DETECT AF PRO) Noé BrasierChristina J. RaichleMarcus Dörr2018 год

Detection of atrial fibrillation with a smartphone camera: first prospective, international, two-centre, clinical validation study (DETECT AF PRO)
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Аннотация: Early detection of atrial fibrillation (AF) is essential for stroke prevention. Emerging technologies such as smartphone cameras using photoplethysmography (PPG) and mobile, internet-enabled electrocardiography (iECG) are effective for AF screening. This study compared a PPG-based algorithm against a cardiologist's iECG diagnosis to distinguish between AF and sinus rhythm (SR). In this prospective, two-centre, international, clinical validation study, we recruited in-house patients with presumed AF and matched controls in SR at two university hospitals in Switzerland and Germany. In each patient, a PPG recording on the index fingertip using a regular smartphone camera followed by iECG was obtained. Photoplethysmography recordings were analysed using an automated algorithm and compared with the blinded cardiologist's iECG diagnosis. Of 672 patients recruited, 80 were excluded mainly due to insufficient PPG/iECG quality, leaving 592 patients (SR: n = 344, AF: n = 248). Based on 5 min of PPG heart rhythm analysis, the algorithm detected AF with a sensitivity of 91.5% (95% confidence interval 85.9–95.4) and specificity of 99.6% (97.8–100). By reducing analysis time to 1 min, sensitivity was reduced to 89.9% (85.5–93.4) and specificity to 99.1% (97.5–99.8). Correctly classified rate was 88.8% for 1-min PPG analysis and dropped to 60.9% when the threshold for the analysed file was set to 5 min of good signal quality. This is the first prospective clinical two-centre study to demonstrate that detection of AF by using a smartphone camera alone is feasible, with high specificity and sensitivity. Photoplethysmography signal analysis appears to be suitable for extended AF screening. ClinicalTrials.gov, number NCT02949180, https://clinicaltrials.gov/ct2/show/NCT02949180.
Год издания: 2018
Авторы: Noé Brasier, Christina J. Raichle, Marcus Dörr, Adrian Becke, Vivien Nohturfft, Stefan Weber, Fabienne Bulacher, Lorena Salomon, Thierry Noah, Ralf Birkemeyer, Jens Eckstein
Издательство: Oxford University Press
Источник: EP Europace
Ключевые слова: Atrial Fibrillation Management and Outcomes, Cardiac Arrhythmias and Treatments, ECG Monitoring and Analysis
Другие ссылки: EP Europace (PDF)
EP Europace (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
PubMed (HTML)