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A History of thePharmacologicalTreatment of BipolarDisorder Francisco López‐MuñozWinstonW ShenPilar D’Ocón2018 год

A History of the Pharmacological Treatment of Bipolar Disorder
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: In this paper, the authors review the history of the pharmacological treatment of bipolar disorder, from the first nonspecific sedative agents introduced in the 19th and early 20th century, such as solanaceae alkaloids, bromides and barbiturates, to John Cade’s experiments with lithium and the beginning of the so-called “Psychopharmacological Revolution” in the 1950s. We also describe the clinical studies and development processes, enabling the therapeutic introduction of pharmacological agents currently available for the treatment of bipolar disorder in its different phases and manifestations. Those drugs include lithium salts, valproic acid, carbamazepine, new antiepileptic drugs, basically lamotrigine and atypical antipsychotic agents (olanzapine, risperidone, quetiapine, ziprasidone, aripiprazole, asenapine, cariprazine and lurasidone). Finally, the socio-sanitary implications derived from the clinical introduction of these drugs are also discussed.
Год издания: 2018
Авторы: Francisco López‐Muñoz, WinstonW Shen, Pilar D’Ocón, Alejandro Romero, Cecilio Álamo
Издательство: Multidisciplinary Digital Publishing Institute
Источник: International Journal of Molecular Sciences
Ключевые слова: Bipolar Disorder and Treatment, Schizophrenia research and treatment, Pharmacological Effects and Toxicity Studies
Другие ссылки: International Journal of Molecular Sciences (PDF)
International Journal of Molecular Sciences (HTML)
DOAJ (DOAJ: Directory of Open Access Journals) (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
Library Open Repository (Universidad Complutense Madrid) (PDF)
Library Open Repository (Universidad Complutense Madrid) (HTML)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (PDF)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (HTML)
PubMed (HTML)