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New tools for theanalysis andvalidation of cryo-EMmaps and atomicmodels Pavel V. AfonineBruno P. KlaholzNigel W. Moriarty2018 год

New tools for the analysis and validation of cryo-EM maps and atomic models
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Аннотация: Recent advances in the field of electron cryomicroscopy (cryo-EM) have resulted in a rapidly increasing number of atomic models of biomacromolecules that have been solved using this technique and deposited in the Protein Data Bank and the Electron Microscopy Data Bank. Similar to macromolecular crystallography, validation tools for these models and maps are required. While some of these validation tools may be borrowed from crystallography, new methods specifically designed for cryo-EM validation are required. Here, new computational methods and tools implemented in PHENIX are discussed, including d
Год издания: 2018
Авторы: Pavel V. Afonine, Bruno P. Klaholz, Nigel W. Moriarty, Billy K. Poon, Oleg V. Sobolev, Thomas C. Terwilliger, Paul D. Adams, Alexandre Urzhumtsev
Источник: Acta Crystallographica Section D Structural Biology
Ключевые слова: Advanced Electron Microscopy Techniques and Applications, Electron and X-Ray Spectroscopy Techniques, Crystallography and Radiation Phenomena
Другие ссылки: Acta Crystallographica Section D Structural Biology (PDF)
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