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QuantifyingPublication Bias inMeta-Analysis Lifeng LinHaitao Chu2017 год

Quantifying Publication Bias in Meta-Analysis
статья из журнала

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Publication bias is a serious problem in systematic reviews and meta-analyses, which can affect the validity and generalization of conclusions. Currently, approaches to dealing with publication bias can be distinguished into two classes: selection models and funnel-plot-based methods. Selection models use weight functions to adjust the overall effect size estimate and are usually employed as sensitivity analyses to assess the potential impact of publication bias. Funnel-plot-based methods include visual examination of a funnel plot, regression and rank tests, and the nonparametric trim and fill method. Although these approaches have been widely used in applications, measures for quantifying publication bias are seldom studied in the literature. Such measures can be used as a characteristic of a meta-analysis; also, they permit comparisons of publication biases between different meta-analyses. Egger's regression intercept may be considered as a candidate measure, but it lacks an intuitive interpretation. This article introduces a new measure, the skewness of the standardized deviates, to quantify publication bias. This measure describes the asymmetry of the collected studies' distribution. In addition, a new test for publication bias is derived based on the skewness. Large sample properties of the new measure are studied, and its performance is illustrated using simulations and three case studies.
Год издания: 2017
Авторы: Lifeng Lin, Haitao Chu
Издательство: Oxford University Press
Источник: Biometrics
Ключевые слова: Meta-analysis and systematic reviews, Diverse Approaches in Healthcare and Education Studies, Reliability and Agreement in Measurement
Другие ссылки: Biometrics (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
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