Physical Activity And Markers Of Inflammation In Childrenстатья из журнала
Аннотация: Inflammatory markers have been linked to adiposity, atherosclerosis and risk factors for development of cardiovascular disease. Regular physical activity (PA) is associated with potential benefits for many health outcomes. However, few studies have examined the associations between objectively assessed PA and inflammatory markers in healthy children. Moreover, these studies often include small sample sizes and few inflammatory markers. PURPOSE: To examine the associations of objectively measured overall PA (counts per minute, CPM), moderate-to-vigorous PA (MVPA) and vigorous PA (VPA) with markers of inflammation in children. METHODS: Of the 1467 children invited in 2005-2006, 1306 children participated, giving an overall participation rate of 89%. Inflammatory markers were; C-reactive protein (CRP), leptin, adiponektin, plasminogen activator inhibitor-1 (PAI-1), tumor necrosis factor α (TNFα) and interleukin-6 (IL-6). PA was assessed objectively by accelerometry (ActiGraph 7164). Outcomes variabels were overall PA (CPM) as well ass time spent in MVPA (> 2000 CPM) and VPA (> 6000 CPM). We used linear regression analysis to examine the association between PA and inflammatory markers, and one-way analysis of variance to analyze differences between groups. RESULTS: Time spent in VPA was negatively associated with CRP (β = -0,162), PAI-1 (β = -0,138) and leptin (β = -0,208) (p < 0,001 for all) after adjustment for sex. Further, there was a significant negative association between overall PA (CPM) and MVPA with CRP, PAI-1 and leptin (p < 0,05 for all), although the magnitude of association was less pronounced compared with VPA. We observed a graded association of CRP, PAI-1 and leptin across tertiles of VPA (p ≤ 0,01 for all). CONCLUSIONS: Our results show that PA were negatively associated with inflammatory markers in Norwegian nine-year old children. Despite this being a cross-sectional study, the results indicate the importance of overall PA level. The association was most pronounced for VPA, suggesting that vigorous intensity activity may be more beneficial than moderate intensity in relation to inflammatory markers.
Год издания: 2017
Авторы: Runar Barstad Solberg, Sigmund A. Anderssen, Elin Kolle, Ulf Ekelund, Jostein Steene‐Johannessen
Издательство: Lippincott Williams & Wilkins
Источник: Medicine & Science in Sports & Exercise
Ключевые слова: Exercise and Physiological Responses, Adipokines, Inflammation, and Metabolic Diseases, Dietary Effects on Health
Открытый доступ: closed
Том: 49
Выпуск: 5S
Страницы: 165–165