Аннотация:Introduction: It is hypothesized that endocardiac fixation and traction of transvenous implantable cardioverter-defibrillator leads may increase the burden of ventricular arrhythmias in the post implantation period, resulting in more appropriate shocks. The emergence of the subcutaneous ICDs (S-ICDs) without transvenous leads enables objectification. We assessed appropriate therapy in a matched cohort of transvenous and subcutaneous ICD patients. Methods: Patients from two tertiary centers were matched 1:1. S-ICDs implanted since 2009 at Academic Medical Center (n = 140) were compared to transvenous ICDs (TV-ICDs) from Leiden University Medical Center implanted between 2005-2014 (n = 1014). Propensity matching was performed for 16 baseline characteristics, including diagnosis and indication. Appropriate shock rates at six months follow-up were compared and hazard ratios adjusted for ICD programming were calculated. Results: All 16 baseline characteristics were balanced, with a median age of 41 and 40% females. The appropriate shock rates were equal in both groups with 5.1% for TV-ICDs versus 2.4% for S-ICDs (p = 0.25) (Figure 1).
