Аннотация:AIMTo investigate if the down-regulation of N-myc Downstream Regulated Gene 2 (NDRG2 ) expression in colorectal carcinoma (CRC) is due to loss of the NDRG2 allele(s).February 10, 2017|Volume 8|Issue 1| WJCO|www.wjgnet.com Lorentzen A et al . NDRG2 in colorectal carcinoma CONCLUSIONOur study suggests that the reduction in NDRG2 expression observed in CRC is due to transcriptional repression by MYC and promoter methylation, and is not due to allelic loss.