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Flavonoids: anoverview Archana PancheA D DiwanSheela Chandra2016 год

Flavonoids: an overview
review

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Аннотация: Abstract Flavonoids, a group of natural substances with variable phenolic structures, are found in fruits, vegetables, grains, bark, roots, stems, flowers, tea and wine. These natural products are well known for their beneficial effects on health and efforts are being made to isolate the ingredients so called flavonoids. Flavonoids are now considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications. This is attributed to their anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties coupled with their capacity to modulate key cellular enzyme function. Research on flavonoids received an added impulse with the discovery of the low cardiovascular mortality rate and also prevention of CHD. Information on the working mechanisms of flavonoids is still not understood properly. However, it has widely been known for centuries that derivatives of plant origin possess a broad spectrum of biological activity. Current trends of research and development activities on flavonoids relate to isolation, identification, characterisation and functions of flavonoids and finally their applications on health benefits. Molecular docking and knowledge of bioinformatics are also being used to predict potential applications and manufacturing by industry. In the present review, attempts have been made to discuss the current trends of research and development on flavonoids, working mechanisms of flavonoids, flavonoid functions and applications, prediction of flavonoids as potential drugs in preventing chronic diseases and future research directions.
Год издания: 2016
Авторы: Archana Panche, A D Diwan, Sheela Chandra
Издательство: Cambridge University Press
Источник: Journal of Nutritional Science
Ключевые слова: Phytochemicals and Antioxidant Activities, Natural product bioactivities and synthesis, Natural Antidiabetic Agents Studies
Другие ссылки: Journal of Nutritional Science (PDF)
Journal of Nutritional Science (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
Eprints@CMFRI Open Access Institutional Repository (Central Marine Fisheries Research Institute) (HTML)
PubMed (HTML)