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Obstructive sleepapnoea syndrome andits management Lucia SpicuzzaDaniela CarusoGiuseppe Di Maria2015 год

Obstructive sleep apnoea syndrome and its management
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Obstructive sleep apnoea (OSA) is a common disorder characterized by repetitive episodes of nocturnal breathing cessation due to upper airway collapse. OSA causes severe symptoms, such as excessive daytime somnolence, and is associated with a significant cardiovascular morbidity and mortality. Different treatment options are now available for an effective management of this disease. After more than three decades from its first use, continuous positive airway pressure (CPAP) is still recognized as the gold standard treatment. Nasal CPAP (nCPAP) is highly effective in controlling symptoms, improving quality of life and reducing the clinical sequelae of sleep apnoea. Other positive airway pressure modalities are available for patients intolerant to CPAP or requiring high levels of positive pressure. Mandibular advancement devices, particularly if custom made, are effective in mild to moderate OSA and provide a viable alternative for patients intolerant to CPAP therapy. The role of surgery remains controversial. Uvulopalatopharyngoplasty is a well established procedure and can be considered when treatment with CPAP has failed, whereas maxillar-mandibular surgery can be suggested to patients with a craniofacial malformation. A number of minimally invasive procedures to treat snoring are currently under evaluation. Weight loss improves symptoms and morbidity in all patients with obesity and bariatric surgery is an option in severe obesity. A multidisciplinary approach is necessary for an accurate management of the disease.
Год издания: 2015
Авторы: Lucia Spicuzza, Daniela Caruso, Giuseppe Di Maria
Издательство: SAGE Publishing
Источник: Therapeutic Advances in Chronic Disease
Ключевые слова: Obstructive Sleep Apnea Research, Tracheal and airway disorders, Neuroscience of respiration and sleep
Другие ссылки: Therapeutic Advances in Chronic Disease (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
PubMed (HTML)