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Dengue: etiology ofacute febrile illnessin Abidjan, Côted'Ivoire, in2011–2012 Maïna L’AzouTiphanie SuccoMamadou Kamagaté2015 год

Dengue: etiology of acute febrile illness in Abidjan, Côte d'Ivoire, in 2011–2012
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Аннотация: The burden of dengue in Africa is not well understood. A prospective study was conducted in Abidjan, Côte d'Ivoire from December 2011 to December 2012 to estimate the proportion of dengue and malaria cases among febrile patients during a period when dengue was not known to be circulating in the region, and to describe the clinical and virological characteristics of laboratory-diagnosed dengue cases.Blood samples were taken from febrile patients (body temperature ≥ 38°C) at two study sites. Patients with fever lasting more than 7 days, with fever of known origin and with jaundice were excluded. Thick blood film tests, ELISA for anti-dengue IgM and reverse transcription-PCR (RT-PCR) were performed.A total of 812 patients were enrolled (51.7% male [48.3% female]; 46.4% aged <10 years) of whom 796 (98.0%) provided IgM ELISA and RT-PCR data, and 807 (99.4%) had thick blood film results. Three (0.4%) patients had laboratory-diagnosed dengue (one with DENV-3 serotype), none of whom were diagnosed clinically, and 234 (28.8%) had confirmed malaria.This study suggests that dengue virus circulates in Abidjan outside an epidemic and that there should be an increase in awareness of dengue as a possible diagnosis in cases of undifferentiated fever. These results stress the importance of implementing laboratory capacity to assess dengue burden in Africa.
Год издания: 2015
Авторы: Maïna L’Azou, Tiphanie Succo, Mamadou Kamagaté, Abdoulaye Ouattara, Elia Gilbernair, Edgar Adjogoua, Christine Luxemburger
Издательство: Oxford University Press
Источник: Transactions of the Royal Society of Tropical Medicine and Hygiene
Ключевые слова: Mosquito-borne diseases and control, Malaria Research and Control, Viral Infections and Vectors
Другие ссылки: Transactions of the Royal Society of Tropical Medicine and Hygiene (PDF)
Transactions of the Royal Society of Tropical Medicine and Hygiene (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
PubMed (HTML)