Аннотация:Abstract Summary: We have developed a new method (BioHMM) for segmenting array comparative genomic hybridization data into states with the same underlying copy number. By utilizing a heterogeneous hidden Markov model, BioHMM incorporates relevant biological factors (e.g. the distance between adjacent clones) in the segmentation process. Availability: BioHMM is available as part of the R library snapCGH which can be downloaded from Contact: J.Marioni@damtp.cam.ac.uk Supplementary information: Supplementary information is available at
