1. Главная
  2. Ресурсы
  3. Библиотечный поиск
Regional differencesof vitamin Ddeficiency inrheumatoid arthritispatients in Italy Maurizio RossiniG. D'AvolaMaurizio Muratore2013 год

Regional differences of vitamin D deficiency in rheumatoid arthritis patients in Italy
статья из журнала

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Vitamin D deficiency is very common in patients with rheumatoid arthritis (RA). Aim of this study was to evaluate the prevalence of vitamin D deficiency among the different Italian regions and whether these variations are associated with different severity of the disease. The study includes 581 consecutive RA patients (464 women), not taking vitamin D supplements, from 22 Italian rheumatology centres uniformly distributed across Italy. Together with parameters of disease activity (disease activity score 28), functional impairment (activities of daily living and health assessment questionnaire disability index) and mean sun exposure time, all patients had serum 25-hydroxyvitamin D (25OHD) measured in a centralized laboratory. Vitamin D deficiency (25OHD level <20 ng/mL) was very frequent among RA patients; its prevalence was 60%, 52% and 38% in southern, central and northern Italy, respectively. Mean disease activity and disability scores were worse in southern regions of Italy. These scores were inversely related to 25OHD levels and this correlation remained statistically significant after adjusting for both body mass index (BMI) and sun exposure time. However, disease severity remained significantly higher in southern regions versus central-northern Italy after adjustment also for serum 25OHD levels, age and BMI. In RA Italian patients there are significant regional differences in the prevalence of vitamin D deficiency explained by different BMI, and sun exposure time, and inversely associated with disease activity and disability scores.
Год издания: 2013
Авторы: Maurizio Rossini, G. D'Avola, Maurizio Muratore, Nazzarena Malavolta, F Silveri, Gerolamo Bianchi, Bruno Frediani, Giovanni Minisola, M Sorgi, M. Varenna, Rosario Foti, G. Tartarelli, Giovanni Orsolini, S. Adámi
Издательство: PAGEPress (Italy)
Источник: Reumatismo
Ключевые слова: Vitamin D Research Studies, Microscopic Colitis, Psoriasis: Treatment and Pathogenesis
Другие ссылки: Reumatismo (PDF)
Reumatismo (HTML)
UNICA IRIS Institutional Research Information System (University of Cagliari) (PDF)
UNICA IRIS Institutional Research Information System (University of Cagliari) (HTML)
Florence Research (University of Florence) (PDF)
Florence Research (University of Florence) (HTML)
Iris Unimore (University of Modena and Reggio Emilia) (PDF)
Iris Unimore (University of Modena and Reggio Emilia) (HTML)
Institutional Research Information System University of Turin (University of Turin) (PDF)
Institutional Research Information System University of Turin (University of Turin) (HTML)
Use Siena air (University of Siena) (PDF)
Use Siena air (University of Siena) (HTML)
PubMed (HTML)