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Survival in PatientsWith Uveal Melanomain Europe Gianni Virgili2008 год

Survival in Patients With Uveal Melanoma in Europe
статья из журнала

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Аннотация:

Objective

To estimate survival in patients in whom uveal melanoma was diagnosed between January 1, 1983, and December 31, 1994, in Europe.

Methods

Survival analysis of data from 32 cancer registries in 16 European countries adhering to the European Cancer Registry for 5788 patients with uveal melanoma diagnosed between January 1, 1983, and December 31, 1994, with follow-up to 1999.

Results

Five-year relative survival was 68.9% overall and remained stable with the period of diagnosis. Relative excess risk of death was 2.45 (95% confidence interval [CI], 2.10-2.86) in patients aged 75 years or older compared with patients aged 54 years or younger and was slightly higher in male patients (relative excess risk, 1.10; 95% CI, 1.02-1.19) than in female patients. Survival was similar in Nordic countries (relative excess risk, 1.03; 95% CI, 0.87-1.21) compared with the United Kingdom (reference country) and was lower in eastern and western European countries (1.26; 1.05-1.52, and 1.25; 0.90-1.60, respectively) compared with the reference country.

Conclusions

In this large series of patients with uveal melanoma, 5-year relative survival remained stable with the introduction of conservative treatment in individuals in whom uveal melanoma was diagnosed between 1983 and 1994. We found differences in survival between sexes and in European areas that should be investigated in studies that consider tumor characteristics at the individual level.
Год издания: 2008
Авторы: Gianni Virgili
Издательство: American Medical Association
Источник: Archives of Ophthalmology
Ключевые слова: Ocular Oncology and Treatments, melanin and skin pigmentation, Retinal Development and Disorders
Другие ссылки: Archives of Ophthalmology (HTML)
HAL (Le Centre pour la Communication Scientifique Directe) (HTML)
HAL (Le Centre pour la Communication Scientifique Directe) (HTML)
LSHTM Research Online (London School of Hygiene and Tropical Medicine) (HTML)
PubMed (HTML)