Functional food science and gastrointestinal physiology and functionreview
Аннотация: Abstract The gut is an obvious target for the development of functional foods, acting as it does as the interface between diet and the metabolic events which sustain life. The key processes in digestive physiology which can be regulated by modifying diet are satiety, the rate and extent of macronutrient breakdown and absorption from the small bowel, sterol metabolism, the colonic microflora, fermentation, mucosal function and bowel habit, and the gut immune system. The intestinal microflora is the main focus of many current functional foods. Probiotics are foods which contain live bacteria which are beneficial to health whilst prebiotics, such as certain non-digestible oligosaccharides which selectively stimulate the growth of bifidobacteria in the colon, are already on the market. Their claimed benefits are to alleviate lactose maldigestion, increase resistance to invasion by pathogenic species of bacteria in the gut, stimulate the immune system and possibly protect against cancer. There are very few reports of well-designed human intervention studies with prebiotics as yet. Certain probiotic species have been shown to shorten the duration of rotavirus diarrhoea in children but much more work is needed on the mechanism of immunomodulation and of competitive exclusion and microflora modification. The develop-ment of functional foods for the gut is in its infancy and will be successful only if more fundamental research is done on digestive physiology, the gut microflora, immune system and mucosal function.
Год издания: 1998
Авторы: Seppo Salminen, C. Bouley, M C Boutron, J.H. Cummings, A. Franck, Glenn R. Gibson, Erika Isolauri, Marie-Christiane Moreau, Marcel Roberfroid, Ian Rowland
Издательство: Cambridge University Press
Источник: British Journal Of Nutrition
Ключевые слова: Microbial Metabolites in Food Biotechnology, Digestive system and related health, Infant Nutrition and Health
Другие ссылки: British Journal Of Nutrition (PDF)
British Journal Of Nutrition (HTML)
HAL (Le Centre pour la Communication Scientifique Directe) (HTML)
PubMed (HTML)
British Journal Of Nutrition (HTML)
HAL (Le Centre pour la Communication Scientifique Directe) (HTML)
PubMed (HTML)
Открытый доступ: bronze
Том: 80
Выпуск: S1
Страницы: S147–S171