1. Главная
  2. Ресурсы
  3. Библиотечный поиск
Glial cells inneuronal networkfunction Alfonso AraqueMarta Navarrete2010 год

Glial cells in neuronal network function
review

Полный текстСтраница публикацииПубликация в OpenAlex
Аннотация: Numerous evidence demonstrates that astrocytes, a type of glial cell, are integral functional elements of the synapses, responding to neuronal activity and regulating synaptic transmission and plasticity. Consequently, they are actively involved in the processing, transfer and storage of information by the nervous system, which challenges the accepted paradigm that brain function results exclusively from neuronal network activity, and suggests that nervous system function actually arises from the activity of neuron-glia networks. Most of our knowledge of the properties and physiological consequences of the bidirectional communication between astrocytes and neurons resides at cellular and molecular levels. In contrast, much less is known at higher level of complexity, i.e. networks of cells, and the actual impact of astrocytes in the neuronal network function remains largely unexplored. In the present article, we summarize the current evidence that supports the notion that astrocytes are integral components of nervous system networks and we discuss some functional properties of intercellular signalling in neuron-glia networks.
Год издания: 2010
Авторы: Alfonso Araque, Marta Navarrete
Издательство: Royal Society
Источник: Philosophical Transactions of the Royal Society B Biological Sciences
Ключевые слова: Neuroscience and Neuropharmacology Research, Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments
Другие ссылки: Philosophical Transactions of the Royal Society B Biological Sciences (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
PubMed (HTML)