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Risk Factors forMarburg HemorrhagicFever, DemocraticRepublic of the Congo Daniel G. BauschMatthias BorchertThomas Grein2003 год

Risk Factors for Marburg Hemorrhagic Fever, Democratic Republic of the Congo
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Аннотация: We conducted two antibody surveys to assess risk factors for Marburg hemorrhagic fever in an area of confirmed Marburg virus transmission in the Democratic Republic of the Congo. Questionnaires were administered and serum samples tested for Marburg-specific antibodies by enzyme-linked immunosorbent assay. Fifteen (2%) of 912 participants in a general village cross-sectional antibody survey were positive for Marburg immunoglobulin G antibody. Thirteen (87%) of these 15 were men who worked in the local gold mines. Working as a miner (odds ratio [OR] 13.9, 95% confidence interval [CI] 3.1 to 62.1) and receiving injections (OR 7.4, 95% CI 1.6 to 33.2) were associated with a positive antibody result. All 103 participants in a targeted antibody survey of healthcare workers were antibody negative. Primary transmission of Marburg virus to humans likely occurred via exposure to a still unidentified reservoir in the local mines. Secondary transmission appears to be less common with Marburg virus than with Ebola virus, the other known filovirus.
Год издания: 2003
Авторы: Daniel G. Bausch, Matthias Borchert, Thomas Grein, Cathy Roth, Robert Swanepoel, Modeste L. Libande, Antoine Talarmin, E. Bertherat, Jean-Jacques Muyembe-Tamfum, Ben Tugume, Robert Colebunders, Kader M. Kondé, Patricia Pirard, Loku L. Olinda, G Rodier, Patricia T. Campbell, Oyewale Tomori, Thomas G. Ksiazek, Pierre E. Rollin
Издательство: Centers for Disease Control and Prevention
Источник: Emerging infectious diseases
Ключевые слова: Viral Infections and Outbreaks Research, Viral Infections and Vectors, Disaster Response and Management
Другие ссылки: Emerging infectious diseases (PDF)
Emerging infectious diseases (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
LSHTM Research Online (London School of Hygiene & Tropical Medicine) (HTML)
CiteSeer X (The Pennsylvania State University) (PDF)
CiteSeer X (The Pennsylvania State University) (HTML)
PubMed (HTML)