Аннотация:patients treated with preoperative prophylaxis.Because the prophylaxis regimen included a corticosteroid, we monitored our outcomes for wound complications.Although the complication rate was two-fold greater in patients receiving prophylaxis and dye compared with those receiving neither, this was not statistically significant.Several mechanisms of action behind adverse reactions to isosulfan blue dye have been postulated, but none have been confirmed.We are currently investigating the molecular basis of these adverse reactions.