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Hepatitis C virusinfection in 2,744hemodialysis patientsfollowed regularly atnine centers inHiroshima duringNovember 1999 throughFebruary 2003 Junko KumagaiYutaka KomiyaJunko Tanaka2005 год

Hepatitis C virus infection in 2,744 hemodialysis patients followed regularly at nine centers in Hiroshima during November 1999 through February 2003
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Аннотация: Abstract Patients on maintenance hemodialysis (HD) are at increased risk of infection with hepatitis C virus (HCV). A prospective follow‐up study on HCV infection from November 1999 to February 2003 was conducted in nine hemodialysis (HD) units in Hiroshima. A total of 2,744 HD patients were surveyed regularly for HCV RNA in serum. The prevalence of HCV RNA decreased from 15.7% (262/1,664) on the first survey to 12.9% (242/1,882) in the last one ( P < 0.05). This decrease may be attributed to the inclusion of patients with a lower prevalence of HCV RNA compared to patients leaving dialysis centers (111/1,080 [10.3%] vs. 132/862 [15.3%], P < 0.01). During the 40 months of this study, 16 de novo HCV infections were documented in the nine HD units corresponding to an incidence of 0.33% per year. These cases included eight new HCV infections, three re‐infections, and five infections that presumably occured in the window period when tested during the first survey. Our study shows that the annual incidence of de novo HCV infection during HD was 0.33%, and emphasizes the need for frequent serum HCV RNA testing and for stringent disinfection procedures in order to prevent the transmission of HCV in these settings. J. Med. Virol. 76:498–502, 2005. © 2005 Wiley‐Liss, Inc.
Год издания: 2005
Авторы: Junko Kumagai, Yutaka Komiya, Junko Tanaka, Keiko Katayama, Yorimitsu Tatsukawa, Noriaki Yorioka, Yuzo Miyakawa, Hiroshi Yoshizawa
Издательство: Wiley
Источник: Journal of Medical Virology
Ключевые слова: Hepatitis C virus research, Hepatitis B Virus Studies, Renal Transplantation Outcomes and Treatments
Другие ссылки: Journal of Medical Virology (HTML)
PubMed (HTML)