Аннотация:retinopathy 6 and d'Alteroche found hypertension carried a relative risk of 4.60 for developing retinopathy. 1Of course hypertension and diabetes also disrupt microcirculation and can each independently cause retinopathy.We postulate for that for our patient, both interferon and hypertension contributed initially to retinopathy.By reducing blood pressure, the total amount of microcirculation injury was reduced even though effects of interferon remain unchanged, thus improving retinopathy.In patients who develop symptomatic interferon retinopathy, if benefits of interferon treatment outweigh the impact of visual impairment, interferon may be continued.Hypertension and diabetes mellitus should be optimised to reduce retinal microcirculation injury load.Retinopathy may improve once these risk factors have been optimally controlled.Retinopathy should be closely monitored for progression.