Аннотация:The present work deals with the synthesis of some novel azo derivatives of dihydropyrimidinones. The structures of newly synthesized compounds were established on the basis of their FTIR, 1H NMR, Mass spectrometry and elemental analysis data results. The synthesized agents were assessed for their in vivo anti-inflammatory activity on the Wistar albino rats. The compounds were also screened for their anthelmintic activity on Indian earthworms and anti-bacterial activity against some Gram-positive and Gram-negative strains of bacteria. This pharmacological activity appraisal unveils that among all the compounds screened, compounds 4b, 4c and 4g were found to have potential anti-inflammatory activity. Furthermore, compounds 4b and 4c exhibited appreciable anthelmintic properties while compounds 4b and 4d showed leading anti-bacterial activity against the selected pathogenic strains of bacteria.
