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Hair-root lead toscreen for leadtoxicity James R. CampbellT. Y. Toribara2001 год

Hair-root lead to screen for lead toxicity
статья из журнала

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Аннотация: The objective of ths study was o determine the validity of a hair-root lead level for the screening of elevated blood lead levels. Children who required a screening blood lead level were eligible for enrollment. After consent, a venipuncture blood sample was obtained from each child and, concurrently, three to five hair samples were plucked from the scalp. All telogen hairs and samples without a hair-root sheath were discarded. Two samples were assayed using X-ray fluorescence spectrometry: one was from a child with a blood lead level of 1 μg/dL and the second was from a child with a blood lead level of 54 μg/dL. A total of 148 hair-root samples were obtained. Only 59 (40%) had a hair-root sheath. The average elemental count, which is a measure of the amount of lead at the position of the hair-root being measured, was 313 for a child with a blood lead level of 1 μg/dL and 266 for a child with a blood lead level of 54 μg/dL. These counts are very low, essentially the same, and very close to the background counts. The findings of this study do not support the use of hair-root samples for the screening of elevated blood lead levels. J. Trace Elem. Exp. Med. 14:69–72, 2001. © 2001 Wiley-Liss, Inc.
Год издания: 2001
Авторы: James R. Campbell, T. Y. Toribara
Издательство: Wiley
Источник: The Journal of Trace Elements in Experimental Medicine
Ключевые слова: Heavy Metal Exposure and Toxicity, Contact Dermatitis and Allergies, Immunotoxicology and immune responses