CONTRAST EXTRAVASATION ON CT ANGIOGRAPHY PREDICTS HEMATOMA EXPANSION IN INTRACEREBRAL HEMORRHAGEписьмо
Аннотация: Background: Patients with acute intracerebral hemorrhage (ICH) presenting within 3 hours of symptom onset are known to be at increased risk of expansion. However, only a minority arrive within this time frame. Therefore, alternative markers for expansion risk are needed. Objective: To examine whether contrast extravasation on CT angiography (CTA) at presentation predicts subsequent hematoma expansion. Methods: Consecutive patients with primary ICH presenting to an urban tertiary care hospital were prospectively captured in a database. We retrospectively reviewed images for all patients receiving a CTA and at least one further CT scan within 48 hours. Results: Complete data were available for 104 patients. Contrast extravasation at the time of CTA was present in 56% of patients, and associated with an increased risk of hematoma expansion (22% vs 2%, p = 0.003). Patients who received a baseline CTA within 3 hours were more likely to have subsequent expansion (27%, vs 13% for those presenting later, p = 0.1). However, after multivariable analysis, contrast extravasation was the only significant predictor of hematoma expansion (OR 18, 95% CI 2.1 to 162). This effect was independent of time to presentation. Conclusions: Contrast extravasation is independently associated with hematoma expansion. Patients presenting within the first few hours after symptom onset have traditionally been considered those at highest risk of expansion. However, for those presenting later, the presence of contrast may be a useful marker to guide therapies aimed at decreasing this risk.
Год издания: 2007
Авторы: Yasuo Murai, Yukio Ikeda, Akira Teramoto
Издательство: Lippincott Williams & Wilkins
Источник: Neurology
Ключевые слова: Intracerebral and Subarachnoid Hemorrhage Research, Acute Ischemic Stroke Management, Neurosurgical Procedures and Complications
Открытый доступ: closed
Том: 69
Выпуск: 6
Страницы: 617–617