Аннотация:equivalent numbers of hypertetraploid cells (BPH: 1.3 k 0.9%; abnormal diploid: 10.8 k 5.4%; tetraploid: 11.1 f 6.8% hypertetraploid cells).Thus, the authors propose that abnormal diploid cancers represent an early stage in ploidy progression.DNA ploidy abnormalities also occur in benign prostatic tissue adjacent to many prostate cancers, consistent with the concept that human prostatic cancer is a field-change disease.Cancer 1993;
