Аннотация:Abstract A microplant, starting from monomers to produce polymer particles, is described and integrates polymerization reaction, polymer analysis and nanoparticle formation in a single continuous‐flow microprocess. Original contribution is brought by online polymer analysis and inline polymer nanoprecipitation. Multi‐detection GPC of samples taken at the outlet of the microreactor actually enables the characterization of linear and branched polymers by combining a concentration‐ and a mass‐sensitive detection technique. When the steady state of the microreactor is reached, micromixer‐assisted nanoprecipitation of the polymer solution follows, leading to a colloidal suspension of nanoparticles with a narrow particle size distribution. Particle sizes, around 100 nm, can be tuned by process parameters. magnified image
Ключевые слова:Innovative Microfluidic and Catalytic Techniques Innovation, Microfluidic and Capillary Electrophoresis Applications, 3D Printing in Biomedical Research
