The Iowa Gambling Task in fMRI imagesстатья из журнала
Аннотация: Abstract The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision‐making impairments in several neurological and psychiatric populations. Very few studies have employed the IGT in functional magnetic resonance imaging (fMRI) investigations, in part, because the task is cognitively complex. Here we report a method for exploring brain activity using fMRI during performance of the IGT. Decision‐making during the IGT was associated with activity in several brain regions in a group of healthy individuals. The activated regions were consistent with the neural circuitry hypothesized to underlie somatic marker activation and decision‐making. Specifically, a neural circuitry involving the dorsolateral prefrontal cortex (for working memory), the insula and posterior cingulate cortex (for representations of emotional states), the mesial orbitofrontal and ventromedial prefrontal cortex (for coupling the two previous processes), the ventral striatum and anterior cingulate/SMA (supplementary motor area) for implementing behavioral decisions was engaged. These results have implications for using the IGT to study abnormal mechanisms of decision making in a variety of clinical populations. Hum Brain Mapp, 2010. © 2009 Wiley‐Liss, Inc.
Год издания: 2009
Авторы: Xiangrui Li, Zhong‐Lin Lu, Arnaud D’Argembeau, Marie Ng, Antoine Bechara
Издательство: Wiley
Источник: Human Brain Mapping
Ключевые слова: Functional Brain Connectivity Studies, Neural and Behavioral Psychology Studies, Neural dynamics and brain function
Другие ссылки: Human Brain Mapping (HTML)
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Europe PMC (PubMed Central) (PDF)
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Open Repository and Bibliography (University of Liège) (PDF)
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PubMed (HTML)
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Том: 31
Выпуск: 3
Страницы: 410–423