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The synapsin cycle: Aview from thesynaptic endocyticzone Emma EvergrenFabio BenfenatiOleg Shupliakov2007 год

The synapsin cycle: A view from the synaptic endocytic zone
review

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Аннотация: Abstract Although the synapsin phosphoproteins were discovered more than 30 years ago and are known to play important roles in neurotransmitter release and synaptogenesis, a complete picture of their functions within the nerve terminal is lacking. It has been shown that these proteins play an important role in the clustering of synaptic vesicles (SVs) at active zones and function as modulators of synaptic strength by acting at both pre‐ and postdocking levels. Recent studies have demonstrated that synapsins migrate to the endocytic zone of central synapses during neurotransmitter release, which suggests that there are additional functions for these proteins in SV recycling. © 2007 Wiley‐Liss, Inc.
Год издания: 2007
Авторы: Emma Evergren, Fabio Benfenati, Oleg Shupliakov
Издательство: Wiley
Источник: Journal of Neuroscience Research
Ключевые слова: Cellular transport and secretion, Lipid Membrane Structure and Behavior, Neuroscience and Neuropharmacology Research
Другие ссылки: Journal of Neuroscience Research (HTML)
PubMed (HTML)