Аннотация:Eradication of Pseudomonas aeruginosa in cystic fibrosis patientsTo the Editors:We share the opinion that the optimal therapeutic strategy to eradicate Pseudomonas aeruginosa from the airways of patients with cystic fibrosis (CF) is still unclear.This situation is not likely to change by comparing small studies employing different methodologies in different settings, particularly our study [1] with that of EBER et al. [2].Clearly, larger studies have to be undertaken to provide a better basis for a consensus in this context.We do not share the opinion of EBER et al.[2] that ''true eradication'' of P. aeruginosa is not proven in our study.Knowing that throat/sputum cultures might be false-negative, we typed sequential P. aeruginosa isolates from CF patients and demonstrated that the majority of P. aeruginosa strains, isolated after eradication therapy and a period with negative throat/ sputum cultures, were indeed genotypically different from the initial strains.Similar results have also been obtained from other investigators [3].
