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American Associationof ClinicalEndocrinologists(AACE) ConsensusConference on theInsulin ResistanceSyndrome Zachary T. Bloomgarden2003 год

American Association of Clinical Endocrinologists (AACE) Consensus Conference on the Insulin Resistance Syndrome
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Аннотация: This is the first of two articles on the American Association of Clinical Endocrinologists (AACE) consensus conference on the insulin resistance syndrome (IRS), which was held in Washington, DC, on 25–26 August 2002. (See http://www.aace.com/pub/irscc/findings.php for summary.) Woody Kessel (Washington, DC), the Deputy Surgeon General, introduced the conference, by discussing “leading health indicators,” including physical activity, reduction of overeating, drug abuse, attention to sexual health, mental health, environmental health, injury prevention, and provision of access to care. The lifestyle factors underlying the metabolic syndrome are, he pointed out, highly prominent factors on this list. Earl S. Ford (Atlanta, GA) discussed public health aspects of the IRS. He characterized “public health” as engaging not only in the assessment and in monitoring of the health of communities, but also in the formulation of public policies and the assurance of access to health care. Addressing the question of whether the IRS is a public health problem, he pointed to its high prevalence and its association with increased morbidity and mortality. Persons with the IRS show higher all-cause mortality, cardiovascular disease (CVD), diabetes, polycystic ovary syndrome (PCOS), and nonalcoholic steatohepatitis (NASH). The syndrome is likely to be very costly, with estimates that the related condition, obesity, leads to health costs in the U.S. of $100 billion yearly. Ford cited proposed AACE criteria defining persons as having the IRS if they do not have diabetes and if they meet two or more of the criteria of triglyceride ≥150 mg/dl, HDL <40 or 50 in men or women, respectively, blood pressure ≥130/85 mmHg or current use of antihypertensive medications, and 2-h glucose 140–199 mg/dl (with postload rather than fasting glucose chosen as being of greater sensitivity). He applied these criteria to data from the third National Health and Nutrition Evaluation Survey (NHANES III) carried out in …
Год издания: 2003
Авторы: Zachary T. Bloomgarden
Издательство: American Diabetes Association
Источник: Diabetes Care
Ключевые слова: Diabetes, Cardiovascular Risks, and Lipoproteins, Hyperglycemia and glycemic control in critically ill and hospitalized patients, Cardiovascular Function and Risk Factors
Другие ссылки: Diabetes Care (PDF)
Diabetes Care (HTML)
PubMed (HTML)