The “New” Head and Neck Cancer Patient—Young, Nonsmoker, Nondrinker, and HPV Positive: Evaluationreview
Аннотация: Objective The near epidemic rise of the incidence of human papillomavirus (HPV)‐related oropharyngeal squamous cell carcinomas (OPSCC) presents the practitioner with a “new” head and neck cancer patient, vastly different from those with the traditional risk factors who formed the basis of most practitioners’ training experience. Accordingly, a thorough and disease‐specific evaluation process is necessitated. This article will review the evaluation of the HPV‐related cancer patient, including a review of the HPV‐positive oropharyngeal cancer epidemic from the surgeon's perspective, evaluation of the primary lesion, evaluation of the neck mass, and role of imaging, to provide a framework for addressing the challenging questions patients may ask. Data Sources Available peer‐reviewed literature and practice guidelines. Review Methods Assessment of selected specific topics by authors solicited from the Head and Neck Surgery and Oncology Committee of the American Academy of Otolaryngology—Head and Neck Surgery Foundation and the American Head and Neck Society. Conclusions and Implications for Practice The dramatic rise in OPSSC related to HPV is characterized by a “new” cancer patient who is younger and lacks traditional risk factors. Today's caregiver must be prepared to appropriately evaluate, counsel, and treat these patients with HPV‐positive disease with the expectation that traditional treatment algorithms will evolve to maintain or improve current excellent cure rates while lessening treatment related side effects.
Год издания: 2014
Авторы: Daniel G. Deschler, Jeremy D. Richmon, Samir S. Khariwala, Robert L. Ferris, Marilene B. Wang
Издательство: Wiley
Источник: Otolaryngology
Ключевые слова: Head and Neck Cancer Studies, Cancer Diagnosis and Treatment, Cervical Cancer and HPV Research
Другие ссылки: Otolaryngology (HTML)
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Europe PMC (PubMed Central) (HTML)
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eScholarship (California Digital Library) (PDF)
eScholarship (California Digital Library) (HTML)
PubMed (HTML)
Europe PMC (PubMed Central) (PDF)
Europe PMC (PubMed Central) (HTML)
PubMed Central (HTML)
eScholarship (California Digital Library) (PDF)
eScholarship (California Digital Library) (HTML)
PubMed (HTML)
Открытый доступ: green
Том: 151
Выпуск: 3
Страницы: 375–380