Аннотация:Hydrogen bonding makes a difference: Multifunctional primary amine catalysts derived from cinchona alkaloids are used in the highly enantioselective 1,3-dipolar cycloaddition of cyclic enones and azomethine imines (see scheme; R=aryl, alkyl; TIPBA=2,4,6-triisopropylbenzenesulfonic acid). The synergistic hydrogen-bonding interaction of catalyst and 1,3-dipole is essential for stereocontrol. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z702618_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
