Аннотация:We thank Farooki and Schneider (1) for their comments on our recently published article (2) on diabetes treatments and cancer-related mortality. As we had indicated (2), we agree with Drs. Farooki and Schneider that additional clinical data would aid our understanding of pathophysiologic mechanisms. Clinical intervention studies may be optimal in obtaining such pathophysiologic data. However, such studies may be impractical given the large numbers of patients required …